ST. LOUIS – Tony La Russa was hoping for a line-drive single or a sacrifice fly. Aaron Miles, too.

Instead, he shocked the San Diego Padres with power.

Miles’ grand slam in the ninth inning, the first game-ending hit of his career, helped the St. Louis Cardinals recover from another blown save by Jason Isringhausen in a 9-5 victory over San Diego on Sunday that wrapped up a four-game sweep.

The 5-foot-8, 175-pound Miles has only seven homers in three seasons with the Cardinals.

“That’s a feeling I wasn’t sure I was going to get to experience, that walk-off homer,” Miles said. “I’ve never done it before, not in the minor leagues or on any field. That’s a great feeling.”

Troy Glaus’ three-run homer off Heath Bell in the eighth gave the Cardinals a two-run lead but the Padres rallied against Isringhausen, who blew his eighth save in 19 chances. He was booed by a sellout crowd after allowing three straight one-out hits, including an RBI double by Edgar Gonzalez.

Isringhausen got the shot at his first save since May 5 because replacement closer Ryan Franklin, who is 14-for-18, needed a day off after a two-inning save on Saturday.

“No matter how much a veteran he is, he’s trying to do more,” La Russa said. “And today, it was less.”

Brad Thompson (2-2) allowed a tying RBI double by Kevin Kouzmanoff before retiring Luke Carlin and Adrian Gonzalez with the bases loaded. The Cardinals swept a four-game series from the Padres for the first time since July 1990 and earned their first four-game sweep against any opponent since beating the Dodgers in July 2006.

Cha Seung Baek pitched into the seventh and added his first career home run for the Padres, who have lost six in a row and have been swept five times in series of three or more games. Scott Hairston hit his fourth career leadoff homer, three coming this year.

The Padres coughed up a five-run lead Saturday and a three-run cushion Friday, and led 3-1 after six innings Sunday.

“Hey, we’ve got to keep playing,” manager Bud Black said. “You saw us come back after going down two runs in the ninth. That can be demoralizing, but I think you saw our team bounced back.”

Bryan Corey (1-2) walked Albert Pujols on four pitches with one out in the ninth and Pujols went to third on a wild pickoff throw by catcher Carlin, an eighth-inning substitute. Pinch-hitter Yadier Molina and Skip Schumaker were walked to load the bases before Miles hit his second career slam, and only his third homer of the season, on a 2-1 pitch.

It was the franchise’s 10th game-ending grand slam, and first since Gary Bennett beat the Cubs on Aug. 27, 2006.

Black said Carlin, a rookie who made it to the majors because of injuries to Michael Barrett and Josh Bard, got “caught up in the moment.”

“I saw him get way off the bag, but the pitch is up and I’ve got to hold onto the ball,” Carlin said.