DETROIT – Jermaine Dye and Paul Konerko reached 300 career homers with consecutive drives in the second inning as the Chicago White Sox beat the Detroit Tigers 10-6 on Monday.

Carlos Quentin went 4-for-4 with two homers and four RBIs for the White Sox, who earned their third straight win. Dye went 3-for-5, and Konerko finished with four hits and three RBIs.

Dye and Konerko became the first teammates to hit century milestone home runs of at least 300 in the same game, according to Elias Sports Bureau.

Ramon Santiago hit a three-run homer and Josh Anderson had three RBIs for Detroit, which had won three straight. Santiago finished with three hits.

Dye hit a 2-1 pitch from Zach Miner (1-1) over the wall in left-center leading off the second. Konerko went deep on a full-count offering to make it 2-0. It was the second homer of the year for both.

The White Sox added four more in the third. Quentin singled in a run, Konerko doubled in a pair and Alexei Ramirez’s RBI single made it 6-1.

Miner allowed eight runs and nine hits, including three homers, in three 1-3 innings.

Gavin Floyd (1-1) lasted five innings to get the win. He gave up six runs and five hits, walked seven and struck out two.

D.J. Carrasco, Matt Thornton and Scott Linebrink combined for four scoreless relief innings.

Santiago’s two-out drive in the third cut Chicago’s lead to 6-4 but Quentin responded with a two-run shot in the fourth. He hit his fourth homer of the season in the sixth and Konerko doubled in Dye to make it 10-6.

Anderson singled in a run in the second for his first hit and RBI with the Tigers. He also had a two-run double in the fifth.